Migraine is a common cause of headaches in adults. Population-based studies indicate that between 12% and 16% of people suffer from migraine headaches, with women being affected three times as often as men. Migraine headaches can be so severe that they can prevent the sufferer from carrying out her or his usual activities for many hours or days.

The causes of such headaches are not completely understood, but most researchers believe they stem from a combination of genetic, neurochemical, and vascular mechanisms.

Following are some typical features of migraine headaches:

• A first sign may be a combination of warning signals before the headache appears, such as nausea or flashing lights.
• The headache itself is usually throbbing in character.
• It may involve only part of the head, such as one side.
• It may last for hours to days.
• It may be accompanied by some of the warning signs mentioned above, such as nausea or visual difficulties.
• Light and noise may make it worse.

Many people with migraines receive little relief from over-the-counter pain medications. Fortunately, newer agents appear to be making advances in the treatment of migraine. Summit Research has conducted a number of trials of some of these investigational medications.

Migraine Checklist / Apply for Study